- The ProLego server application explores the component (SSE) and topology aspect of Protein Structure space. It investigates the modularity in protein structures using in-house developed contact string
- Duration: Apr 2016 to Oct 2018
- People: Indira Ghosh , Shailesh Kumar Panday , Taushif Khan
- Database(s): ProLegoDB
- Funding: DBT
The ProLego server application explores the component aspect of Protein Structure space. ProLego, investigates the modularity in protein structures using in-house developed "contact string" (A Topological representation)Protein building blocks as an analogy to "Lego® bricks"
Legos are small and simple components used to build various shapes. From our extensive analysis of available protein structure space, we have shown that protein structures are composed of smaller building blocks or "modules". These modules can be used as "lego-blocks" for investigation and(or) designing new proteins.Why "Pro-Lego"?
With Pro-Lego, we provide an application that generates the protein topology string (or contact string) and a platform to vizualise in simple topological graphs. Encompassing the analysis on non-redundant protein structure data sets, we also list the variation in topological space (ProLegoDB).